Best Supplement Shopify Agencies for Vitamins & Supplement Brands

The global vitamins and minerals market has reached a staggering $34.24 billion, with vitamins leading as the primary supplement for two-thirds of the global online population.

With only 17% of consumers avoiding supplements entirely, the window for eCommerce growth is wide open.

As a result, competition for digital shelf space has intensified, with Shopify store counts surging by 125% in 2024 and an additional 42.04% in 2025.

This requires integrating transparent product information, robust UX, and seamless repeat-purchase models that align with the specific needs of health-conscious audiences.

Partnering with a dedicated supplement Shopify agency ensures your store meets the unique demands of the wellness sector, from ingredient transparency to seamless subscriptions.

Their experience helps supplement brands in driving conversions and competing effectively in a crowded digital marketplace.

Choosing the right partner starts with understanding their unique strengths.

Below is a strategic breakdown of the industry’s leading supplement Shopify agencies.

Use this table for a quick alignment check before we dive into the full technical profiles later in this guide.

craftberry is a boutique Shopify Plus agency with an in-house team of 30+ experienced e-commerce experts specializing in the supplement, health and wellness industry.

While partnering with brands across multiple verticals, craftberry has built proven expertise in the supplement sector.

We help supplement brands and health-conscious consumers connect through high-performing Shopify stores.

Our team delivers visually compelling online supplement stores that balance lifestyle imagery, product quality with conversion rate optimization to boost sales, increase average order value, and retain customers in the supplement industry.

If you’re a supplement brand owner looking to scale, craftberry’s deep experience in the wellness space helps your Shopify store meet industry-specific demands.

This approach drives sustainable growth, as proven by success with established brands in the niche.

• Custom Theme Development to create unique storefronts that showcase product benefits, ingredient transparency, and brand voice

• Strategic Shopify Consultation for data-driven insights to improve CRO, AOV stacks for higher average order value and long-term growth

• Headless & App Development for tailored shopping experiences, private apps, product bundles, and loyalty programs

• Shopify CRO Services to optimize your supplement Shopify store and increase sales

• Continuous Maintenance to ensure fast, secure, and scalable e-commerce operations for customers.

Notable Clients: Midi, Innermost, ArthroFill and more

Location: Bulgaria (partnering with brands globally).

Sunrise Integration is a Shopify Plus Partner with over 20 years of experience in high-end enterprise development and complex systems architecture.

As dedicated Shopify consultants for supplement e-commerce, they build Shopify stores for your brand by focusing on:

• Advanced API & System Integrations to connect your storefront with ERPs, CRMs, and 3PL logistics providers

• Custom App & Subscription Development to implement complex recurring billing models and "build-your-own-bundle" features that are essential for driving customer engagement

• Data Migration & Infrastructure Architecture to securely transition legacy customer data to Shopify Plus, providing a stable foundation that supports rapid global scaling

• Omnichannel Solutions that unify digital sales and physical retail, creating a unified experience that enhances brand loyalty across all touchpoints.

Notable Clients: OK Capsule, Naturewise, Immunotec and more

Location: USA

blubolt is a premier Shopify Plus agency that empowers brands to shatter eCommerce goals through high-performance, custom-built solutions.

Their portfolio includes over 400 projects, showcasing optimized customer experiences for diverse sectors ranging from protein powder specialists to luxury lifestyle brands.

blubolt empowers brands to elevate their eCommerce presence through a comprehensive suite of specialized services:

• Custom Development to build high-performance, scalable storefronts

• Site Migrations & Redesigns for a seamless transition to Shopify that leverages customer data to create a fresh, modern aesthetic

• UX & CRO Optimization to enhance the customer journey and fine-tune conversion funnels to increase sales

• Growth Strategy Consulting to provide data-driven insights that help brands scale effectively in a competitive market

• Ongoing Support to ensure continuous technical excellence and optimization that drives measurable business results.

Notable Clients: MaxiNutrition and more

Location: the UK

Milk Bottle Labs is Ireland's first fully dedicated Shopify Plus agency.

They specialize in customer-centred, partnership-based solutions designed to guide you toward your ideal ecommerce platform.

Since 2014, Milk Bottle Labs has focused exclusively on helping you succeed by delivering exceptional eCommerce experiences built around the world’s fastest-growing Shopify ecosystem.

Milk Bottle Labs provides performance improvements tailored to the unique challenges of the wellness industry.

Key services:

• Migrate to Shopify for a seamless transition from legacy platforms while preserving your critical customer base, data, purchase history, and SEO integrity

• Grow with Shopify Plus by leveraging enterprise automation to drive growth

• Shopify B2B Services to build specialized portals for wholesale clients, streamlining complex bulk-ordering

• Ongoing Support & Maintenance for brands to ensure peak performance during high-traffic launches and manage complex subscription updates.

Notable Clients: Soundbites, Fabuwellness, Revive Active and more

Location: Ireland

As a Shopify Partner, AMBAUM positions itself not just as developers, but as former merchants who have been in your shoes.

AMBAUM brings real-world ecommerce experience, having built, scaled, and optimized hundreds of brands since 2016 through a combination of strategy, technical leadership, and operational insight.

With a merchant-first approach, the team supports ambitious brands through:

• Fractional CTO guidance

• Custom frontend and backend development

• Theme customization for supplement brands

• Platform migrations.

AMBAUM helps elevate your online presence with services such as strategic technology planning, performance-focused Shopify builds, and custom integrations designed to drive measurable business growth.

Notable Clients: Solv Wellness, Bulletproof Coffee and more

Location: US

Sleepless Media is a nickel-and-dime agency for passionate people who are invested in your results.

As an official Shopify Plus Partner, they deliver custom design and development solutions for online stores, including projects in the health and wellness space.

They focus on bespoke Shopify and Shopify Plus builds, UX/UI optimization, and performance improvements to support long-term ecommerce growth.

Sleepless Media's key services for scaling your store:

• Custom Shopify development for brands to build high-performing online stores

• Strategic design to enhance customer experience

• Ongoing optimization to build customer trust, showcase customer reviews, protect margins, and help shoppers feel confident in their purchase decisions.

Notable Clients: InfiniWell and more

Location: US

Simplistic is a results‑driven Shopify Plus Platinum agency and Shopify experts for vitamin shops.

Their focus is on streamlining the entire ecommerce process to ensure your experience is seamless, simple, and straightforward.

With a business‑first perspective, the team approaches your ecommerce like you would, cutting through the clutter to help your brand achieve meaningful growth.

Simplistic helps brands scale their Shopify stores with optimized performance and usability.

They ensure a smooth experience while focusing on strategic development and operational efficiency.

Simplistic's Shopify solutions for nutrition stores:

• Online Store Design & development to build high-performing websites

• Conversion Rate Optimization (CRO) for Supplement Brands to drive conversions

• Data Analytics & Outsourced Site Management to improve efficiency

• SEO & e-mail marketing to streamline operations and repeat purchases.

Notable Clients: cbdMD, Neuro, Ritual and more

Location: US

Coldsmoke is a certified Shopify Plus Partner agency known for building high-performance, custom ecommerce experiences that push boundaries for ambitious brands.

Combining gritty determination with innovation, they align technical expertise with your business goals.

This is achieved through a collaborative, strategy-first approach.

Coldsmoke helps your brand elevate its online presence and achieve long-term growth through:

• Platform Migrations & Integrations to transition your store seamlessly while implementing custom APIs and complex subscription systems with zero data loss

• Headless Commerce Solutions to deliver unmatched speed, design flexibility, and a superior mobile experience

• Custom Shopify Plus Development with bespoke themes and high-performance architecture built for scale and reliability

• Customer Engagement & Optimization to drive loyalty through personalized shopping experiences and data-driven retention strategies.

Notable Clients: Coromega

Location: US

Hyper Effect is a certified Shopify Plus Partner that bridges the gap between innovative brand storytelling and technical commerce excellence.

They prioritize a "people-first" philosophy, specializing in scaling e-commerce businesses that have a positive impact on human well-being.

Hyper Effect builds high-converting Shopify supplement stores designed for long-term growth through:

• CX Design & User Empathy to align your digital roadmap with real-world human needs through intuitive, user-friendly interfaces that drive critical KPI goals

• High-End Shopify Plus Development to build world-class, scalable storefronts that prioritize a seamless customer journey and reflect the premium nature of your products

• CRO to analyze buyer behavior and implement data-driven improvements that maximize customer engagement and lifetime value

• Customer Loyalty & Growth Partnerships to expand your digital footprint through effective retention strategies and programs that keep users committed to their wellness journey.

Notable Clients: MOST Elements and more

Location: Poland

THAILS is a Shopify agency that supports businesses with Shopify store development and e-commerce design. The agency works with a range of brands, with a focus on skincare products and premium-oriented online storefronts.

Their role typically includes building and maintaining Shopify sites and providing ongoing support as a partner throughout the store lifecycle.

They deliver Shopify stores that are visually engaging, technically robust, and optimized for sustainable growth.

Their methodology focuses on balancing the scientific credibility essential for supplement consumers with a frictionless, modern and seamless experience.

Key expertise for health and wellness brands:

• Custom Shopify Development to drive results of your online store

• Data-Led UX & CRO to identify and remove friction points to stabilize and scale conversion rates

• Subscription Integration to implement recurring payment systems and maximize customer lifetime value

• Migration Services to transfer stores seamlessly while protecting data, product pages, and functionality

• Scalable E-commerce Strategy to provide ongoing support and guidance for expanding product lines and entering new markets.

Notable Clients: Vivo Life, My Way Up, and more

Location: the Netherlands

• Regulatory Compliance & Ad Restrictions

Brands face rigorous scrutiny from platforms like Google and Meta.

Phrasing health benefits such as immune support for various health and wellness products without triggering account suspensions requires a delicate balance between high-conversion copywriting and strict adherence to FDA/FTC guidelines.

• High-Risk Payment Processing

Due to elevated chargeback rates and legal nuances, standard processors often flag supplement stores.

Success depends on integrating specialized high-risk gateways and robust subscription models that ensure financial stability and foster repeat business without service interruptions.

• Technical Trust & Transparency

Scaling in a crowded market demands advanced backend functionality to capture new growth opportunities.

Brands must automate complex tasks like batch tracking, expiration management, and the display of Certificates of Analysis (COAs) to build the consumer trust necessary for long-term loyalty.

This requires integrating transparent product details, robust UX, and seamless repeat purchase models that align with the specific needs of wellness-focused audiences.

Midi partnered with craftberry to develop a high-performance Shopify Plus storefront tailored to the unique needs of women navigating perimenopause and menopause.

To establish Midi as a leader in the clinical wellness space, craftberry focused on a seamless integration of medical credibility and premium e-commerce functionality:

• Custom Shopify Storefront to provide a familiar experience for their loyal client base while selling products, using a design language that felt soft, honest, and warm

• Subscription Model & Loyalty Program Optimization to drive recurring revenue and long-term brand loyalty

• Data-Driven UI/UX Design focused on simplifying the customer journey for health-conscious consumers

• Complex Third-Party Integrations including clinical platforms and specialized health systems

• Trust & Compliance Implementation to ensure scientific authority and transparency.

The project became a seamless extension of the Midi ecosystem, bridging the gap between clinical healthcare and e-commerce.

By unifying education and commerce into a single flow, the site drives higher sales by guiding customers intuitively from learning to purchase while fostering long-term trust.

ArthroFill collaborated with craftberry to elevate their digital presence and streamline the shopping experience for their premium nutritional supplements.

Strengthening Arthrofill’s position in the competitive joint health market, craftberry's team focused on balancing clinical transparency with a high-conversion, premium aesthetic:

• Shopify Platform Migration preserving all data, reviews, subscriptions, and purchase history, while seamlessly onboarding internal teams

• UI/UX Design that anticipates customer questions, reduces friction, and builds confidence to complete a purchase

• Bespoke Shopify Development with custom logic for dynamic subscription options directly in the cart, giving customers full flexibility and control

• Navigation & User Journey Optimization to effortlessly guide health-conscious consumers toward the right joint health solutions

• Trust & Social Proof Integration to build credibility through customer reviews and transparent quality certifications.

The results highlight a successful transformation into a modern, trust-driven e-commerce platform that simplifies the purchasing process while supporting the brand's long-term growth and customer retention goals.

Innermost partnered with craftberry to transition their award-winning nutrition brand to a high-performance Shopify environment.

Focused on elevating storytelling and store performance, we balanced a bold, modern aesthetic with high-level functional excellence:

• Seamless Shopify Plus Migration & Internationalization to provide a robust foundation for international growth and high-volume traffic

• Custom UX & UI Design to simplify the selection process across various functional health goals like energy, recovery, and focus

• Advanced Subscription & Bundle Integration to foster deeper customer relationships and drive higher customer lifetime value

• Strategic Page Optimization to enhance social proof through user-generated content, reducing purchase hesitation and building immediate buyer confidence.

The results deliver a world-class digital storefront that balances functional efficiency with a lifestyle-led brand experience.

It drives a 68% AOV increase, 40% returning customer rate, scalable subscriptions, cross-border growth, and measurable UX improvements.

In 2026, the cost of building a Shopify supplement store depends on technical complexity and scaling goals.

With recent research showing average Shopify store earnings around $67,000, high-growth wellness brands often exceed this baseline through recurring subscription revenue.

• Startups typically invest $5,000–$10,000 for template-based solutions with basic subscription modules to validate their niche

• Growing D2C brands should expect to spend $20,000–$50,000 for bespoke UX/UI design, custom cart logic, and advanced loyalty integrations

• Enterprise migrations to Shopify Plus, featuring complex data transfers and internationalization, often start at $70,000.

A high-quality build is justified by the fact that health products are one of the top performing product categories for your Shopify store

Offering immense potential, these products drive high average order value (AOV) and customer lifetime value.

Choose a partner with a proven track record in the high-stakes wellness industry, not just general e-commerce expertise.

To scale effectively, many brands seek out Shopify plus experts for vitamin brands who understand the technical complexities of enterprise-level health stores.

To identify a partner with the necessary technical depth, many brands consult a curated list of the best Shopify agencies that specialize in high-growth health and wellness brands.

A qualified agency should:

• Prioritize mobile-first navigation and frictionless checkout flows to cater to the 30% of global consumers who now purchase health products online

• Showcase "Trust Economy" expertise by seamlessly integrating social proof, transparent sourcing, and compliance certifications into the UX

• Possess technical proficiency in subscription-first architectures, as recurring revenue models are essential for any successful brand

• Offer comprehensive data migration services to preserve customer history, active subscriptions, and other critical information during the transition.

Theme customization for supplements must go beyond aesthetics to prioritize science-first storytelling and instant authority.

High-converting stores require custom-built modules to display nutritional facts and purity certifications without compromising the user interface.

To achieve the right balance of information and conversion, you can draw inspiration from the best Shopify product page examples.

That inspiration demonstrates how you can organize complex data points into a seamless shopping experience.

Effective customization focuses on mobile optimization by implementing sticky buttons and simplified comparison tables for shoppers on the go.

By integrating dynamic elements like tiered discounts and bundle logic directly into the theme, brands guide users toward higher-value purchases.

In the health and wellness niche, CRO is about engineering a journey of clinical trust and effortless decision-making.

High-performing stores use data-driven strategies to address specific consumer anxieties regarding ingredient transparency and product efficacy.

You can adapt conversion tactics from the best Shopify agencies for beauty stores.

These experts specialize in using lifestyle-driven social proof and high-impact visual storytelling to drive sales

By streamlining the transition from educational content to purchase, Shopify agencies can significantly reduce friction on information-heavy product pages.

Key CRO focus areas for wellness brands include:

• Social Proof Amplification. Integrating verified photo, video reviews and user-generated content to build community-driven credibility

• Frictionless Cart Logic. Highlighting subscription savings and free-shipping progress bars directly within the slide-out cart

• Mobile-First Clarity. Ensuring dense nutritional data and "science-backed" claims remain readable and accessible on small screens

• Upsell Optimization. A/B testing bundle configurations to identify the most persuasive "Value Pack" offers.

Launching a store is just the beginning.

Sustained growth requires proactive maintenance to ensure subscription APIs and logistics integrations remain stable.

Continuous performance monitoring is critical, as any dip in speed can directly hurt search rankings and revenue generation.

Beyond technical fixes, dedicated support includes:

• Security & Compliance. Keeping your storefront updated with evolving data privacy laws and payment standards

• Scale Management. Preparing your infrastructure for high-traffic influencer launches or seasonal sales

• Iterative Enhancements. Rolling out new features based on real-time user data and heatmapping

• App Ecosystem Audits. Optimizing your Shopify app stack to maintain peak loading speeds.

A long-term partnership with trusted Shopify agency ensures your technical foundation remains robust, allowing you to focus entirely on product innovation.

1. Revenue in the vitamins & minerals segment worldwide from 2016 to 2029

2. Most consumed food supplements worldwide 2025.